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Transcriptional programs of lymphoid tissue capillary and high endothelium reveal control mechanisms for lymphocyte homing

Lymphocytes are recruited from blood by high-endothelial venules (HEVs). We performed transcriptomic analyses and identified molecular signatures that distinguish HEVs from capillary endothelium and that define tissue-specific HEV specialization. Capillaries displayed gene programs for vascular deve...

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Detalles Bibliográficos
Autores principales: Lee, Mike, Kiefel, Helena, LaJevic, Melissa D., Macauley, Matthew S., Kawashima, Hiroto, O'Hara, Edward, Pan, Junliang, Paulson, James C., Butcher, Eugene C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222088/
https://www.ncbi.nlm.nih.gov/pubmed/25173345
http://dx.doi.org/10.1038/ni.2983