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Republished: Tracing PAKs from GI inflammation to cancer

P-21 activated kinases (PAKs) are effectors of Rac1/Cdc42 which coordinate signals from the cell membrane to the nucleus. Activation of PAKs drive important signalling pathways including mitogen activated protein kinase, phospoinositide 3-kinase (PI3K/AKT), NF-κB and Wnt/β-catenin. Intestinal PAK1 e...

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Detalles Bibliográficos
Autores principales: Dammann, Kyle, Khare, Vineeta, Gasche, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222351/
https://www.ncbi.nlm.nih.gov/pubmed/25335797
http://dx.doi.org/10.1136/postgradmedj-2014-306768rep