Autonomous assembly of synthetic oligonucleotides built from an expanded DNA alphabet. Total synthesis of a gene encoding kanamycin resistance

Background: Many synthetic biologists seek to increase the degree of autonomy in the assembly of long DNA (L-DNA) constructs from short synthetic DNA fragments, which are today quite inexpensive because of automated solid-phase synthesis. However, the low information density of DNA built from just f...

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Detalles Bibliográficos
Autores principales: Merritt, Kristen K, Bradley, Kevin M, Hutter, Daniel, Matsuura, Mariko F, Rowold, Diane J, Benner, Steven A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222377/
https://www.ncbi.nlm.nih.gov/pubmed/25383105
http://dx.doi.org/10.3762/bjoc.10.245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222377/
https://www.ncbi.nlm.nih.gov/pubmed/25383105
http://dx.doi.org/10.3762/bjoc.10.245

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