Cargando…

Gold(I)-catalysed synthesis of a furan analogue of thiamine pyrophosphate

An analogue of thiamine having a furan ring in place of the thiazolium ring has been synthesised by a short and efficient route, involving gold(I)-catalysed cyclisation of an alkynyl alcohol to form the furan ring. The furan analogue of thiamine diphosphate (ThDP) was also made and tested for bindin...

Descripción completa

Detalles Bibliográficos
Autores principales: Iqbal, Amjid, Sahraoui, El-Habib, Leeper, Finian J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222410/
https://www.ncbi.nlm.nih.gov/pubmed/25383130
http://dx.doi.org/10.3762/bjoc.10.270