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Gold(I)-catalysed synthesis of a furan analogue of thiamine pyrophosphate
An analogue of thiamine having a furan ring in place of the thiazolium ring has been synthesised by a short and efficient route, involving gold(I)-catalysed cyclisation of an alkynyl alcohol to form the furan ring. The furan analogue of thiamine diphosphate (ThDP) was also made and tested for bindin...
Autores principales: | Iqbal, Amjid, Sahraoui, El-Habib, Leeper, Finian J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222410/ https://www.ncbi.nlm.nih.gov/pubmed/25383130 http://dx.doi.org/10.3762/bjoc.10.270 |
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