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The Krüppel-like factor 2 and Krüppel-like factor 4 genes interact to maintain endothelial integrity in mouse embryonic vasculogenesis

BACKGROUND: Krüppel-like Factor 2 (KLF2) plays an important role in vessel maturation during embryonic development. In adult mice, KLF2 regulates expression of the tight junction protein occludin, which may allow KLF2 to maintain vascular integrity. Adult tamoxifen-inducible Krüppel-like Factor 4 (K...

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Detalles Bibliográficos
Autores principales: Chiplunkar, Aditi R, Curtis, Benjamin C, Eades, Gabriel L, Kane, Megan S, Fox, Sean J, Haar, Jack L, Lloyd, Joyce A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222490/
https://www.ncbi.nlm.nih.gov/pubmed/24261709
http://dx.doi.org/10.1186/1471-213X-13-40