Cargando…
Estimating HIV-1 Fitness Characteristics from Cross-Sectional Genotype Data
Despite the success of highly active antiretroviral therapy (HAART) in the management of human immunodeficiency virus (HIV)-1 infection, virological failure due to drug resistance development remains a major challenge. Resistant mutants display reduced drug susceptibilities, but in the absence of dr...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222584/ https://www.ncbi.nlm.nih.gov/pubmed/25375675 http://dx.doi.org/10.1371/journal.pcbi.1003886 |