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Estimating HIV-1 Fitness Characteristics from Cross-Sectional Genotype Data

Despite the success of highly active antiretroviral therapy (HAART) in the management of human immunodeficiency virus (HIV)-1 infection, virological failure due to drug resistance development remains a major challenge. Resistant mutants display reduced drug susceptibilities, but in the absence of dr...

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Detalles Bibliográficos
Autores principales: Gopalakrishnan, Sathej, Montazeri, Hesam, Menz, Stephan, Beerenwinkel, Niko, Huisinga, Wilhelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222584/
https://www.ncbi.nlm.nih.gov/pubmed/25375675
http://dx.doi.org/10.1371/journal.pcbi.1003886