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Drosophila melanogaster as a model organism for Alzheimer’s disease

Drosophila melanogaster provides an important resource for in vivo modifier screens of neurodegenerative diseases. To study the underlying pathogenesis of Alzheimer’s disease, fly models that address Tau or amyloid toxicity have been developed. Overexpression of human wild-type or mutant Tau causes...

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Detalles Bibliográficos
Autores principales: Prüßing, Katja, Voigt, Aaron, Schulz, Jörg B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222597/
https://www.ncbi.nlm.nih.gov/pubmed/24267573
http://dx.doi.org/10.1186/1750-1326-8-35