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Stability Depends on Positive Autoregulation in Boolean Gene Regulatory Networks

Network motifs have been identified as building blocks of regulatory networks, including gene regulatory networks (GRNs). The most basic motif, autoregulation, has been associated with bistability (when positive) and with homeostasis and robustness to noise (when negative), but its general importanc...

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Detalles Bibliográficos
Autores principales: Pinho, Ricardo, Garcia, Victor, Irimia, Manuel, Feldman, Marcus W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222607/
https://www.ncbi.nlm.nih.gov/pubmed/25375153
http://dx.doi.org/10.1371/journal.pcbi.1003916