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Systematic Analysis of the Role of RNA-Binding Proteins in the Regulation of RNA Stability
mRNA half-lives are transcript-specific and vary over a range of more than 100-fold in eukaryotic cells. mRNA stabilities can be regulated by sequence-specific RNA-binding proteins (RBPs), which bind to regulatory sequence elements and modulate the interaction of the mRNA with the cellular RNA degra...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222612/ https://www.ncbi.nlm.nih.gov/pubmed/25375137 http://dx.doi.org/10.1371/journal.pgen.1004684 |