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Systematic Analysis of the Role of RNA-Binding Proteins in the Regulation of RNA Stability

mRNA half-lives are transcript-specific and vary over a range of more than 100-fold in eukaryotic cells. mRNA stabilities can be regulated by sequence-specific RNA-binding proteins (RBPs), which bind to regulatory sequence elements and modulate the interaction of the mRNA with the cellular RNA degra...

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Detalles Bibliográficos
Autores principales: Hasan, Ayesha, Cotobal, Cristina, Duncan, Caia D. S., Mata, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222612/
https://www.ncbi.nlm.nih.gov/pubmed/25375137
http://dx.doi.org/10.1371/journal.pgen.1004684