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Clinicopathological significance and potential drug target of p15(INK4B) in multiple myeloma

Multiple myeloma (MM) is a clonal malignancy characterized by the proliferation of malignant plasma cells in the bone marrow and the production of monoclonal immunoglobulin. In addition to genetic changes, gene hypermethylation is an alternative mechanism of tumor suppressor gene inactivation in MM....

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Detalles Bibliográficos
Autores principales: Li, Jun, Bi, Lintao, Lin, Yumei, Lu, Zhenxia, Hou, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222634/
https://www.ncbi.nlm.nih.gov/pubmed/25382971
http://dx.doi.org/10.2147/DDDT.S71088