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RPN2 Gene Confers Osteosarcoma Cell Malignant Phenotypes and Determines Clinical Prognosis

Drug resistance and metastasis are lethal characteristics of tumors. We previously demonstrated that silencing of ribophorin II (RPN2), which is part of the N-oligosaccharyl transferase complex, efficiently induced apoptosis and reduced resistance to docetaxel in human breast cancer cells. Here, we...

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Detalles Bibliográficos
Autores principales: Fujiwara, Tomohiro, Takahashi, Ryou-u, Kosaka, Nobuyoshi, Nezu, Yutaka, Kawai, Akira, Ozaki, Toshifumi, Ochiya, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222647/
https://www.ncbi.nlm.nih.gov/pubmed/25181275
http://dx.doi.org/10.1038/mtna.2014.35