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Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets

Genetic and epigenetic mechanisms may interact and together affect biological processes and disease development. However, most previous studies have investigated genetic and epigenetic mechanisms independently, and studies examining their interactions throughout the human genome are lacking. To iden...

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Detalles Bibliográficos
Autores principales: Olsson, Anders H., Volkov, Petr, Bacos, Karl, Dayeh, Tasnim, Hall, Elin, Nilsson, Emma A., Ladenvall, Claes, Rönn, Tina, Ling, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222689/
https://www.ncbi.nlm.nih.gov/pubmed/25375650
http://dx.doi.org/10.1371/journal.pgen.1004735