Eplerenone attenuated cardiac steatosis, apoptosis and diastolic dysfunction in experimental type-II diabetes

BACKGROUND: Cardiac steatosis and apoptosis are key processes in diabetic cardiomyopathy, but the underlying mechanisms have not been elucidated, leading to a lack of effective therapy. The mineralocorticoid receptor blocker, eplerenone, has demonstrated anti-fibrotic actions in the diabetic heart....

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Detalles Bibliográficos
Autores principales: Ramírez, Elisa, Klett-Mingo, Mercedes, Ares-Carrasco, Sara, Picatoste, Belén, Ferrarini, Alessia, Rupérez, Francisco J, Caro-Vadillo, Alicia, Barbas, Coral, Egido, Jesús, Tuñón, José, Lorenzo, Óscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222723/
https://www.ncbi.nlm.nih.gov/pubmed/24261558
http://dx.doi.org/10.1186/1475-2840-12-172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222723/
https://www.ncbi.nlm.nih.gov/pubmed/24261558
http://dx.doi.org/10.1186/1475-2840-12-172

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