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Engineering Attenuated Virulence of a Theileria annulata–Infected Macrophage
Live attenuated vaccines are used to combat tropical theileriosis in North Africa, the Middle East, India, and China. The attenuation process is empirical and occurs only after many months, sometimes years, of in vitro culture of virulent clinical isolates. During this extensive culturing, attenuate...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222746/ https://www.ncbi.nlm.nih.gov/pubmed/25375322 http://dx.doi.org/10.1371/journal.pntd.0003183 |