Two novel mutations of pfdhps K540T and I588F, affecting sulphadoxine-pyrimethamine-resistant response in uncomplicated falciparum malaria at Banjar district, South Kalimantan Province, Indonesia

BACKGROUND: Mutations in pfdhfr and pfdhps genes have been shown to associate with sulphadoxine-pyrimethamine (SP) resistance of Plasmodium falciparum parasites. However, pfdhfr, pfdhps genotypes and the correlations to SP treatment outcome in Indonesia has not yet been well analysed. METHODS: After...

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Detalles Bibliográficos
Autores principales: Basuki, Sukmawati, Fitriah, Riyanto, Sugeng, Budiono, Dachlan, Yoes P, Uemura, Haruki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222776/
https://www.ncbi.nlm.nih.gov/pubmed/25187019
http://dx.doi.org/10.1186/1475-2875-13-135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222776/
https://www.ncbi.nlm.nih.gov/pubmed/25187019
http://dx.doi.org/10.1186/1475-2875-13-135

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