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The Role of Wnt/β-Catenin Signaling in Enterocyte Turnover during Methotrexate-Induced Intestinal Mucositis in a Rat

BACKGROUND/AIMS: Intestinal mucositis is a common side-effect in patients who receive aggressive chemotherapy. The Wnt signaling pathway is critical for establishing and maintaining the proliferative compartment of the intestine. In the present study, we tested whether Wnt/β-catenin signaling is inv...

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Detalles Bibliográficos
Autores principales: Sukhotnik, Igor, Geyer, Tatiana, Pollak, Yulia, Mogilner, Jorge G., Coran, Arnold G., Berkowitz, Drora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222808/
https://www.ncbi.nlm.nih.gov/pubmed/25375224
http://dx.doi.org/10.1371/journal.pone.0110675