Topical Application of a Platelet Activating Factor Receptor Agonist Suppresses Phorbol Ester-Induced Acute and Chronic Inflammation and Has Cancer Chemopreventive Activity in Mouse Skin

Platelet activating factor (PAF) has long been associated with acute edema and inflammatory responses. PAF acts by binding to a specific G-protein coupled receptor (PAF-R, Ptafr). However, the role of chronic PAF-R activation on sustained inflammatory responses has been largely ignored. We recently...

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Detalles Bibliográficos
Autores principales: Sahu, Ravi P., Rezania, Samin, Ocana, Jesus A., DaSilva-Arnold, Sonia C., Bradish, Joshua R., Richey, Justin D., Warren, Simon J., Rashid, Badri, Travers, Jeffrey B., Konger, Raymond L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222871/
https://www.ncbi.nlm.nih.gov/pubmed/25375862
http://dx.doi.org/10.1371/journal.pone.0111608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222871/
https://www.ncbi.nlm.nih.gov/pubmed/25375862
http://dx.doi.org/10.1371/journal.pone.0111608

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