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Transplantation of ATP7B–Transduced Bone Marrow Mesenchymal Stem Cells Decreases Copper Overload in Rats

BACKGROUND: Recent studies have demonstrated that transplantation of ATP7B-transduced hepatocytes ameliorates disease progression in LEC (Long-Evans Cinnamon) rats, a model of Wilson's disease (WD). However, the inability of transplanted cells to proliferate in a normal liver hampers long-term...

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Detalles Bibliográficos
Autores principales: Chen, Shenglin, Shao, Cunhua, Dong, Tianfu, Chai, Hao, Xiong, Xinkui, Sun, Daoyi, Zhang, Long, Yu, Yue, Wang, Ping, Cheng, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222898/
https://www.ncbi.nlm.nih.gov/pubmed/25375371
http://dx.doi.org/10.1371/journal.pone.0111425