Menthol Inhibits Detrusor Contractility Independently of TRPM8 Activation

Agonists such as icilin and menthol can activate the cool temperature-sensitive ion channel TRPM8. However, biological responses to menthol may occur independently of TRPM8 activation. In the rodent urinary bladder, menthol facilitates the micturition reflex but inhibits muscarinic contractions of t...

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Detalles Bibliográficos
Autores principales: Ramos-Filho, Antonio Celso Saragossa, Shah, Ajay, Augusto, Taize Machado, Barbosa, Guilherme Oliveira, Leiria, Luiz Osorio, de Carvalho, Hernandes Faustino, Antunes, Edson, Grant, Andrew Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222941/
https://www.ncbi.nlm.nih.gov/pubmed/25375115
http://dx.doi.org/10.1371/journal.pone.0111616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222941/
https://www.ncbi.nlm.nih.gov/pubmed/25375115
http://dx.doi.org/10.1371/journal.pone.0111616

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