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Menthol Inhibits Detrusor Contractility Independently of TRPM8 Activation
Agonists such as icilin and menthol can activate the cool temperature-sensitive ion channel TRPM8. However, biological responses to menthol may occur independently of TRPM8 activation. In the rodent urinary bladder, menthol facilitates the micturition reflex but inhibits muscarinic contractions of t...
Autores principales: | Ramos-Filho, Antonio Celso Saragossa, Shah, Ajay, Augusto, Taize Machado, Barbosa, Guilherme Oliveira, Leiria, Luiz Osorio, de Carvalho, Hernandes Faustino, Antunes, Edson, Grant, Andrew Douglas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222941/ https://www.ncbi.nlm.nih.gov/pubmed/25375115 http://dx.doi.org/10.1371/journal.pone.0111616 |
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