Cargando…

Structural Model of the hUbA1-UbcH10 Quaternary Complex: In Silico and Experimental Analysis of the Protein-Protein Interactions between E1, E2 and Ubiquitin

UbcH10 is a component of the Ubiquitin Conjugation Enzymes (Ubc; E2) involved in the ubiquitination cascade controlling the cell cycle progression, whereby ubiquitin, activated by E1, is transferred through E2 to the target protein with the involvement of E3 enzymes. In this work we propose the firs...

Descripción completa

Detalles Bibliográficos
Autores principales: Correale, Stefania, de Paola, Ivan, Morgillo, Carmine Marco, Federico, Antonella, Zaccaro, Laura, Pallante, Pierlorenzo, Galeone, Aldo, Fusco, Alfredo, Pedone, Emilia, Luque, F. Javier, Catalanotti, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223017/
https://www.ncbi.nlm.nih.gov/pubmed/25375166
http://dx.doi.org/10.1371/journal.pone.0112082