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Eribulin Mesylate Targets Human Telomerase Reverse Transcriptase in Ovarian Cancer Cells

Treatment of advanced ovarian cancer involves platinum-based chemotherapy. However, chemoresistance is a major obstacle. Cancer stem cells (CSCs) are thought to be one of the causes of chemoresistance, but the underlying mechanism remains elusive. Recently, human telomerase reverse transcriptase (hT...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Satoko, Maida, Yoshiko, Yasukawa, Mami, Kato, Tomoyasu, Yoshida, Masayuki, Masutomi, Kenkichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223061/
https://www.ncbi.nlm.nih.gov/pubmed/25375122
http://dx.doi.org/10.1371/journal.pone.0112438