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Eribulin Mesylate Targets Human Telomerase Reverse Transcriptase in Ovarian Cancer Cells
Treatment of advanced ovarian cancer involves platinum-based chemotherapy. However, chemoresistance is a major obstacle. Cancer stem cells (CSCs) are thought to be one of the causes of chemoresistance, but the underlying mechanism remains elusive. Recently, human telomerase reverse transcriptase (hT...
Autores principales: | Yamaguchi, Satoko, Maida, Yoshiko, Yasukawa, Mami, Kato, Tomoyasu, Yoshida, Masayuki, Masutomi, Kenkichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223061/ https://www.ncbi.nlm.nih.gov/pubmed/25375122 http://dx.doi.org/10.1371/journal.pone.0112438 |
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