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Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway in a Proteolysis-Dependent Manner

Enveloped viruses need to fuse with a host cell membrane in order to deliver their genome into the host cell. While some viruses fuse with the plasma membrane, many viruses are endocytosed prior to fusion. Specific cues in the endosomal microenvironment induce conformational changes in the viral fus...

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Detalles Bibliográficos
Autores principales: Burkard, Christine, Verheije, Monique H., Wicht, Oliver, van Kasteren, Sander I., van Kuppeveld, Frank J., Haagmans, Bart L., Pelkmans, Lucas, Rottier, Peter J. M., Bosch, Berend Jan, de Haan, Cornelis A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223067/
https://www.ncbi.nlm.nih.gov/pubmed/25375324
http://dx.doi.org/10.1371/journal.ppat.1004502