IFI16 Restricts HSV-1 Replication by Accumulating on the HSV-1 Genome, Repressing HSV-1 Gene Expression, and Directly or Indirectly Modulating Histone Modifications

Interferon-γ inducible factor 16 (IFI16) is a multifunctional nuclear protein involved in transcriptional regulation, induction of interferon-β (IFN-β), and activation of the inflammasome response. It interacts with the sugar-phosphate backbone of dsDNA and modulates viral and cellular transcription...

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Detalles Bibliográficos
Autores principales: Johnson, Karen E., Bottero, Virginie, Flaherty, Stephanie, Dutta, Sujoy, Singh, Vivek Vikram, Chandran, Bala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223080/
https://www.ncbi.nlm.nih.gov/pubmed/25375629
http://dx.doi.org/10.1371/journal.ppat.1004503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223080/
https://www.ncbi.nlm.nih.gov/pubmed/25375629
http://dx.doi.org/10.1371/journal.ppat.1004503

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