Elevated blood pressure, heart rate and body temperature in mice lacking the XLαs protein of the Gnas locus is due to increased sympathetic tone

NEW FINDINGS: What is the central question of this study? Previously, we showed that Gnasxl knock-out mice are lean and hypermetabolic, with increased sympathetic stimulation of adipose tissue. Do these mice also display elevated sympathetic cardiovascular tone? Is the brain glucagon-like peptide-1...

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Detalles Bibliográficos
Autores principales: Nunn, Nicolas, Feetham, Claire H, Martin, Jennifer, Barrett-Jolley, Richard, Plagge, Antonius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2013
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223506/
https://www.ncbi.nlm.nih.gov/pubmed/23748904
http://dx.doi.org/10.1113/expphysiol.2013.073064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223506/
https://www.ncbi.nlm.nih.gov/pubmed/23748904
http://dx.doi.org/10.1113/expphysiol.2013.073064

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