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Adalimumab regulates intracellular TNFα production in patients with rheumatoid arthritis

INTRODUCTION: Adalimumab is a fully human anti–tumor necrosis factor α (anti-TNFα) monoclonal antibody that specifically blocks the interaction of TNFα with its receptors. It binds both soluble and transmembrane TNFα. We hypothesized that blocking these TNFα signals regulates the altered TNFα produc...

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Detalles Bibliográficos
Autores principales: Zamora-Atenza, Carlos, Diaz-Torne, Cesar, Geli, Carme, Diaz-Lopez, Cesar, Ortiz, M Angels, Moya, Patricia, Castellví, Ivan, Nieto, Juan C, Cantó, Elisabet, Casademont, Jordi, Juarez, Candido, Llobet, Josep M, Vidal, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223509/
https://www.ncbi.nlm.nih.gov/pubmed/25037855
http://dx.doi.org/10.1186/ar4615