Low levels of 3,3′-diindolylmethane activate estrogen receptor α and induce proliferation of breast cancer cells in the absence of estradiol

BACKGROUND: 3,3′-diindolylmethane (DIM) is an acid-catalyzed dimer of idole-3-carbinol (I3C), a phytochemical found in cruciferous vegetables that include broccoli, Brussels sprouts and cabbage. DIM is an aryl hydrocarbon receptor (AhR) ligand and a potential anticancer agent, namely for the treatme...

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Detalles Bibliográficos
Autores principales: Marques, Maud, Laflamme, Liette, Benassou, Ines, Cissokho, Coumba, Guillemette, Benoit, Gaudreau, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223525/
https://www.ncbi.nlm.nih.gov/pubmed/25048790
http://dx.doi.org/10.1186/1471-2407-14-524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223525/
https://www.ncbi.nlm.nih.gov/pubmed/25048790
http://dx.doi.org/10.1186/1471-2407-14-524

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