Systematic permutation testing in GWAS pathway analyses: identification of genetic networks in dilated cardiomyopathy and ulcerative colitis

BACKGROUND: Genome wide association studies (GWAS) are applied to identify genetic loci, which are associated with complex traits and human diseases. Analogous to the evolution of gene expression analyses, pathway analyses have emerged as important tools to uncover functional networks of genome-wide...

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Detalles Bibliográficos
Autores principales: Backes, Christina, Rühle, Frank, Stoll, Monika, Haas, Jan, Frese, Karen, Franke, Andre, Lieb, Wolfgang, Wichmann, H-Erich, Weis, Tanja, Kloos, Wanda, Lenhof, Hans-Peter, Meese, Eckart, Katus, Hugo, Meder, Benjamin, Keller, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223581/
https://www.ncbi.nlm.nih.gov/pubmed/25052024
http://dx.doi.org/10.1186/1471-2164-15-622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223581/
https://www.ncbi.nlm.nih.gov/pubmed/25052024
http://dx.doi.org/10.1186/1471-2164-15-622

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