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Low expression of T-cell transcription factor BCL11b predicts inferior survival in adult standard risk T-cell acute lymphoblastic leukemia patients

BACKGROUND: Risk stratification, detection of minimal residual disease (MRD), and implementation of novel therapeutic agents have improved outcome in acute lymphoblastic leukemia (ALL), but survival of adult patients with T-cell acute lymphoblastic leukemia (T-ALL) remains unsatisfactory. Thus, nove...

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Detalles Bibliográficos
Autores principales: Bartram, Isabelle, Gökbuget, Nicola, Schlee, Cornelia, Heesch, Sandra, Fransecky, Lars, Schwartz, Stefan, Stuhlmann, Reingard, Schäfer-Eckhart, Kerstin, Starck, Michael, Reichle, Albrecht, Hoelzer, Dieter, Baldus, Claudia D, Neumann, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223626/
https://www.ncbi.nlm.nih.gov/pubmed/25023966
http://dx.doi.org/10.1186/s13045-014-0051-y