β-catenin(C429S) mice exhibit sterility consequent to spatiotemporally sustained Wnt signalling in the internal genitalia

Wnt/β-catenin signalling regulates numerous developmental and homeostatic processes. Ctnnb1 (also known as β-catenin) is the only protein that transmits signals from various Wnt ligands to downstream genes. In this study, we report that our newly established mouse strain, which harbours a Cys429 to...

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Detalles Bibliográficos
Autores principales: Murata, Takuya, Ishitsuka, Yuichi, Karouji, Kumiko, Kaneda, Hideki, Toki, Hideaki, Nakai, Yuji, Makino, Shigeru, Fukumura, Ryutaro, Kotaki, Hayato, Wakana, Shigeharu, Noda, Tetsuo, Gondo, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223658/
https://www.ncbi.nlm.nih.gov/pubmed/25376241
http://dx.doi.org/10.1038/srep06959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223658/
https://www.ncbi.nlm.nih.gov/pubmed/25376241
http://dx.doi.org/10.1038/srep06959

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