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β-catenin(C429S) mice exhibit sterility consequent to spatiotemporally sustained Wnt signalling in the internal genitalia
Wnt/β-catenin signalling regulates numerous developmental and homeostatic processes. Ctnnb1 (also known as β-catenin) is the only protein that transmits signals from various Wnt ligands to downstream genes. In this study, we report that our newly established mouse strain, which harbours a Cys429 to...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223658/ https://www.ncbi.nlm.nih.gov/pubmed/25376241 http://dx.doi.org/10.1038/srep06959 |