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Ultrafast propagation of β-amyloid fibrils in oligomeric cloud

Interaction between monomer peptides and seeds is essential for clarifying the fibrillation mechanism of amyloid β (Aβ) peptides. We monitored the deposition reaction of Aβ(1–40) peptides on immobilized seeds grown from Aβ(1–42), which caused formation of oligomers in the early stage. The deposition...

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Detalles Bibliográficos
Autores principales: Ogi, Hirotsugu, Fukukshima, Masahiko, Hamada, Hiroki, Noi, Kentaro, Hirao, Masahiko, Yagi, Hisashi, Goto, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223663/
https://www.ncbi.nlm.nih.gov/pubmed/25376301
http://dx.doi.org/10.1038/srep06960