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UbcH10 overexpression increases carcinogenesis and blocks ALLN susceptibility in colorectal cancer

Cyclins are essential for cell proliferation, the cell cycle and tumorigenesis in all eukaryotes. UbcH10 regulates the degradation of cyclins in a ubiquitin-dependent manner. Here, we report that UbcH10 is likely involved in tumorigenesis. We found that cancer cells exposed to n-acetyl-leu-leu-norle...

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Detalles Bibliográficos
Autores principales: Li, Shang-Ze, Song, Yang, Zhang, Hui-Hui, Jin, Bing-Xue, Liu, Yi, Liu, Wen-Bin, Zhang, Xiao-Dong, Du, Run-Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223683/
https://www.ncbi.nlm.nih.gov/pubmed/25376843
http://dx.doi.org/10.1038/srep06910