Effector CD4 T cell transition to memory requires late cognate interactions that induce autocrine IL-2

It is unclear how CD4 T cell memory formation is regulated following pathogen challenge, and when critical mechanisms act to determine effector T cell fate. Here, we report that following influenza infection most effectors require signals from major histocompatibility complex class II molecules and...

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Detalles Bibliográficos
Autores principales: McKinstry, K. Kai, Strutt, Tara M., Bautista, Bianca, Zhang, Wenliang, Kuang, Yi, Cooper, Andrea M., Swain, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223689/
https://www.ncbi.nlm.nih.gov/pubmed/25369785
http://dx.doi.org/10.1038/ncomms6377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223689/
https://www.ncbi.nlm.nih.gov/pubmed/25369785
http://dx.doi.org/10.1038/ncomms6377

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