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The Trp53-Trp53inp1-Tnfrsf10b Pathway Regulates the Radiation Response of Mouse Spermatogonial Stem Cells

Germ cells are thought to exhibit a unique DNA damage response that differs from that of somatic stem cells, and previous studies suggested that Trp53 is not involved in the survival of spermatogonial stem cells (SSCs) after irradiation. Here, we report a critical role for the Trp53-Trp53inp1-Tnfrsf...

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Detalles Bibliográficos
Autores principales: Ishii, Kei, Ishiai, Masamichi, Morimoto, Hiroko, Kanatsu-Shinohara, Mito, Niwa, Ohtsura, Takata, Minoru, Shinohara, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223695/
https://www.ncbi.nlm.nih.gov/pubmed/25358794
http://dx.doi.org/10.1016/j.stemcr.2014.08.006