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Chemical Conversion of Human Fibroblasts into Functional Schwann Cells

Direct transdifferentiation of somatic cells is a promising approach to obtain patient-specific cells for numerous applications. However, conversion across germ-layer borders often requires ectopic gene expression with unpredictable side effects. Here, we present a gene-free approach that allows eff...

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Detalles Bibliográficos
Autores principales: Thoma, Eva C., Merkl, Claudia, Heckel, Tobias, Haab, Rachel, Knoflach, Frederic, Nowaczyk, Corinne, Flint, Nicholas, Jagasia, Ravi, Jensen Zoffmann, Sannah, Truong, Hoa Hue, Petitjean, Pascal, Jessberger, Sebastian, Graf, Martin, Iacone, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223700/
https://www.ncbi.nlm.nih.gov/pubmed/25358782
http://dx.doi.org/10.1016/j.stemcr.2014.07.014