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Bmi1 regulates self-renewal and epithelial to mesenchymal transition in breast cancer cells through Nanog

BACKGROUND: The Bmi1 polycomb ring finger oncogene, a transcriptional repressor belonging to the Polycomb group of proteins plays an important role in the regulation of stem cell self-renewal and is elevated in several cancers. In the current study, we have explored the role of Bmi1 in regulating th...

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Detalles Bibliográficos
Autores principales: Paranjape, Anurag N, Balaji, Sai A, Mandal, Tamoghna, Krushik, Esthelin Vittal, Nagaraj, Pradeep, Mukherjee, Geetashree, Rangarajan, Annapoorni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223733/
https://www.ncbi.nlm.nih.gov/pubmed/25348805
http://dx.doi.org/10.1186/1471-2407-14-785