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Olanzapine induced DNA methylation changes support the dopamine hypothesis of psychosis

BACKGROUND: The dopamine (DA) hypothesis of schizophrenia proposes the mental illness is caused by excessive transmission of dopamine in selected brain regions. Multiple lines of evidence, including blockage of dopamine receptors by antipsychotic drugs that are used to treat schizophrenia, support t...

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Detalles Bibliográficos
Autores principales: Melka, Melkaye G, Castellani, Christina A, Laufer, Benjamin I, Rajakumar, Raj N, O’Reilly, Richard, Singh, Shiva M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223857/
https://www.ncbi.nlm.nih.gov/pubmed/25408910
http://dx.doi.org/10.1186/2049-9256-1-19