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mGluR2/3 blockade produces rapid and long-lasting reversal of anhedonia caused by chronic stress exposure

BACKGROUND: Depression is a prevalent neuropsychiatric disorder that affects an estimated 350 million people worldwide. Currently available treatments for depression are lacking in both speed of onset and efficacy. Recent pharmacological efforts have targeted the glutamatergic neurotransmitter syste...

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Detalles Bibliográficos
Autores principales: Dwyer, Jason M, Lepack, Ashley E, Duman, Ronald S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224009/
https://www.ncbi.nlm.nih.gov/pubmed/25408908
http://dx.doi.org/10.1186/2049-9256-1-15