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Microglial phenotypes and toll-like receptor 2 in the substantia nigra and hippocampus of incidental Lewy body disease cases and Parkinson’s disease patients

Next to α-synuclein deposition, microglial activation is a prominent pathological feature in the substantia nigra (SN) of Parkinson’s disease (PD) patients. Little is known, however, about the different phenotypes of microglia and how they change during disease progression, in the SN or in another b...

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Detalles Bibliográficos
Autores principales: Doorn, Karlijn J, Moors, Tim, Drukarch, Benjamin, van de Berg, Wilma DJ, Lucassen, Paul J, van Dam, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224021/
https://www.ncbi.nlm.nih.gov/pubmed/25099483
http://dx.doi.org/10.1186/s40478-014-0090-1