Computational investigation of potential dosing schedules for a switch of medication from warfarin to rivaroxaban—an oral, direct Factor Xa inhibitor

The long-lasting anticoagulant effect of vitamin K antagonists can be problematic in cases of adverse drug reactions or when patients are switched to another anticoagulant therapy. The objective of this study was to examine in silico the anticoagulant effect of rivaroxaban, an oral, direct Factor Xa...

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Detalles Bibliográficos
Autores principales: Burghaus, Rolf, Coboeken, Katrin, Gaub, Thomas, Niederalt, Christoph, Sensse, Anke, Siegmund, Hans-Ulrich, Weiss, Wolfgang, Mueck, Wolfgang, Tanigawa, Takahiko, Lippert, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224077/
https://www.ncbi.nlm.nih.gov/pubmed/25426077
http://dx.doi.org/10.3389/fphys.2014.00417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224077/
https://www.ncbi.nlm.nih.gov/pubmed/25426077
http://dx.doi.org/10.3389/fphys.2014.00417

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