Platelets Direct Monocyte Differentiation Into Epithelioid-Like Multinucleated Giant Foam Cells With Suppressive Capacity Upon Mycobacterial Stimulation

Background. Epithelioid, foam, and multinucleated giant cells (MNGCs) are characteristics of tuberculosis granulomas, yet the precise genesis and functions of these transformed macrophages are unclear. We evaluated the role of platelets as drivers of macrophage transformation in mycobacterial infect...

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Detalles Bibliográficos
Autores principales: Feng, Yonghong, Dorhoi, Anca, Mollenkopf, Hans-Joachim, Yin, Hongyun, Dong, Zhengwei, Mao, Ling, Zhou, Jun, Bi, Aixiao, Weber, Stephan, Maertzdorf, Jeroen, Chen, Gang, Chen, Yang, Kaufmann, Stefan H. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224136/
https://www.ncbi.nlm.nih.gov/pubmed/24987031
http://dx.doi.org/10.1093/infdis/jiu355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224136/
https://www.ncbi.nlm.nih.gov/pubmed/24987031
http://dx.doi.org/10.1093/infdis/jiu355

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