Cargando…

Population Genetics Inference for Longitudinally-Sampled Mutants Under Strong Selection

Longitudinal allele frequency data are becoming increasingly prevalent. Such samples permit statistical inference of the population genetics parameters that influence the fate of mutant variants. To infer these parameters by maximum likelihood, the mutant frequency is often assumed to evolve accordi...

Descripción completa

Detalles Bibliográficos
Autores principales: Lacerda, Miguel, Seoighe, Cathal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224163/
https://www.ncbi.nlm.nih.gov/pubmed/25213172
http://dx.doi.org/10.1534/genetics.114.167957