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Novel Distal eQTL Analysis Demonstrates Effect of Population Genetic Architecture on Detecting and Interpreting Associations

Mapping expression quantitative trait loci (eQTL) has identified genetic variants associated with transcription rates and has provided insight into genotype–phenotype associations obtained from genome-wide association studies (GWAS). Traditional eQTL mapping methods present significant challenges fo...

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Detalles Bibliográficos
Autores principales: Weiser, Matthew, Mukherjee, Sayan, Furey, Terrence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224177/
https://www.ncbi.nlm.nih.gov/pubmed/25230953
http://dx.doi.org/10.1534/genetics.114.167791