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Novel Distal eQTL Analysis Demonstrates Effect of Population Genetic Architecture on Detecting and Interpreting Associations
Mapping expression quantitative trait loci (eQTL) has identified genetic variants associated with transcription rates and has provided insight into genotype–phenotype associations obtained from genome-wide association studies (GWAS). Traditional eQTL mapping methods present significant challenges fo...
Autores principales: | Weiser, Matthew, Mukherjee, Sayan, Furey, Terrence S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224177/ https://www.ncbi.nlm.nih.gov/pubmed/25230953 http://dx.doi.org/10.1534/genetics.114.167791 |
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