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Plasmid Copy Number Underlies Adaptive Mutability in Bacteria

The origin of mutations under selection has been intensively studied using the Cairns-Foster system, in which cells of an Escherichia coli lac mutant are plated on lactose and give rise to 100 Lac(+) revertants over several days. These revertants have been attributed variously to stress-induced muta...

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Detalles Bibliográficos
Autores principales: Sano, Emiko, Maisnier-Patin, Sophie, Aboubechara, John Paul, Quiñones-Soto, Semarhy, Roth, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224180/
https://www.ncbi.nlm.nih.gov/pubmed/25173846
http://dx.doi.org/10.1534/genetics.114.170068