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Two Cases of Fatal Encephalopathy Related to Ifosfamide: An Adverse Role of Aprepitant?
Ifosfamide is used in the treatment of sarcomas and other tumors. It sometimes provokes encephalopathy, which is a serious complication even if it is usually reversible within 48–72 h after drug cessation. Ifosfamide is required to be activated by hepatic cytochrome P450 (CYP), especially the 3A4 su...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224236/ https://www.ncbi.nlm.nih.gov/pubmed/25408661 http://dx.doi.org/10.1159/000368184 |