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Two Cases of Fatal Encephalopathy Related to Ifosfamide: An Adverse Role of Aprepitant?

Ifosfamide is used in the treatment of sarcomas and other tumors. It sometimes provokes encephalopathy, which is a serious complication even if it is usually reversible within 48–72 h after drug cessation. Ifosfamide is required to be activated by hepatic cytochrome P450 (CYP), especially the 3A4 su...

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Detalles Bibliográficos
Autores principales:	Séjourné, Alice, Noal, Sabine, Boone, Mathieu, Bihan, Céline, Sassier, Marion, Andrejak, Michel, Chauffert, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	S. Karger AG 2014
Materias:	Published online: September, 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224236/ https://www.ncbi.nlm.nih.gov/pubmed/25408661 http://dx.doi.org/10.1159/000368184

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